Autologous oocyte cryopreservation in women and older using minimal stimulation IVF
Modern reproduction uses all the latest developments to enable people, previously considered infertile, to bear and have their own child. One of these methods is oocyte cryopreservation.
Modern reproduction uses all the latest developments to enable people, previously considered infertile, to bear and have their own child. One of these methods is oocyte cryopreservation. It can be used to increase the chances of embryo survival in an IVF program or to preserve the possibility for a woman to become a mother at any age.
Cryopreservation as a Way to Freeze Time
What is oocyte cryopreservation and why is it needed? The essence of the technology lies in the deep freezing of cells and tissues in liquid nitrogen at a temperature of -320° with the possibility of subsequent defrosting and use. All biological processes in the cells stop, the life cycle is put on hold, and this allows the material to be stored for a long time until it is required for conceiving.
In medicine, oocyte cryopreservation is most often used during an in vitro fertilization procedure (IVF) in order to preserve excess embryos for subsequent replanting. In addition, the method is applicable to a number of other indications to preserve fertile sperm or eggs.
The main task of cryopreservation in reproduction is to increase the chances of pregnancy in women who cannot become pregnant in the traditional way for some reason. Modern reproductive science suggests using cryopreservation not only for medical but also for social reasons. Today, many women under 40 are not ready to have children, choosing to first provide a material basis for the unborn offspring. However, they forget that after 30 years, the female body reduces the ability to reproduce. Cryopreservation of fertile eggs at the peak of childbearing age (from 18 to 28 years) will allow a woman to later carry out her own child with virtually no risk of miscarriage.
Both factors of medical and social nature can be considered as indications for oocytes cryopreservation. The following causes are among them:
- preservation of viable ovicell in cancer patients before chemotherapy or radiotherapy, which adversely affect the ability to bear children;
- endometriosis, causing ovarian dysfunction;
- prospects of using an egg in IVF procedures;
- delayed pregnancy, when a woman wants to give birth to a child only after certain achievements in the career field;
- possibility of fertilization with a sperm donor, including those cases when an unmarried woman decides to become a mother.
The process of storing eggs in a frozen form does not adversely affect their viability. Damage can occur only during freezing or thawing. With rapid freezing, the percentage of embryos survival reaches 98%, while slow freezing gives only about 50%.